Article
Subsets of airway myeloid-derived regulatory cells distinguish mild asthma from chronic obstructive pulmonary disease.
The Journal of allergy and clinical immunology - 1 Feb 2015
Deshane Jessy S, Redden David T, Zeng Meiqin, Spell Marion L, Zmijewski Jaroslaw W, Anderson John T, Deshane Rohit J, Gaggar Amit, Siegal Gene P, Abraham Edward, Dransfield Mark T, Chaplin David D
Abstract excerpt
BACKGROUND: Subsets of myeloid-derived regulatory cells (MDRCs), which are phenotypically similar to the myeloid-derived suppressor cells found in patients with cancer, have recently been appreciated as critical regulators of airway inflammation in mouse models of asthma. OBJECTIVE: We test the hypothesis that subsets of airway MDRCs contribute differentially to the inflammatory milieu in human asthma and chronic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.