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Article

Neutrophilic and Pauci-immune Phenotypes in Severe Asthma.

Immunology and allergy clinics of North America - 1 Aug 2016

Panettieri Reynold A

Abstract excerpt

Although 2 T-helper type 2 inflammation evokes airway hyperresponsiveness and narrowing, neutrophilic or pauci-immune asthma accounts for significant asthma morbidity. Viruses, toxicants, environmental tobacco smoke exposure, and bacterial infections induce asthma exacerbations mediated by neutrophilic inflammation or by structural cell (pauci-immune) mechanisms. Therapeutic challenges exist in the management of...

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Identifiers

PMID: 27401627
DOI: 10.1016/j.iac.2016.03.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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