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Article

Differences in systemic adaptive immunity contribute to the 'frequent exacerbator' COPD phenotype.

Respiratory research - 28 Oct 2016

Geerdink Jasper X, Simons Sami O, Pike Rebecca, Stauss Hans J, Heijdra Yvonne F, Hurst John R

Abstract excerpt

BACKGROUND: Some COPD patients are more susceptible to exacerbations than others. Mechanisms underlying these differences in susceptibility are not well understood. We hypothesized that altered cell mediated immune responses may underlie a propensity to suffer from frequent exacerbations in COPD. METHODS: Peripheral blood mononuclear cells (PBMCs) were obtained from 24 stable COPD patients, eight frequent...

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Source

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Identifiers

PMID: 27793198
DOI: 10.1186/s12931-016-0456-y
PMCID: PMC5084432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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