Article
Neutrophilic asthma features increased airway classical monocytes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Feb 2021
Niessen Natalie M, Baines Katherine J, Simpson Jodie L, Scott Hayley A, Qin Ling, Gibson Peter G, Fricker Michael
Abstract excerpt
BACKGROUND: Monocytes and macrophages are critical innate immune cells of the airways. Despite their differing functions, few clinical studies discriminate between them and little is known about their regulation in asthma. OBJECTIVE: We aimed to distinguish and quantify macrophages, monocytes and monocyte subsets in induced sputum and blood and examine their relationship with inflammatory and clinical features of...
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