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Article

Phenotypes of regulatory T cells in different stages of COPD.

International immunopharmacology - 25 Oct 2024

Alves Luan H V, Ito Juliana T, Almeida Francine M, Oliveira Luana M, Stelmach Rafael, Tibério Lolanda F L C, Sato Maria N, Lopes Fernanda D T Q S

Abstract excerpt

BACKGROUND: Previous studies have shown that failure to control inflammatory processes mediated by regulatory T (Treg) cells contributes to chronic obstructive pulmonary disease (COPD) development and progression. The activity of Treg cells depends on their phenotypic characteristics: resting Treg (rTreg, CD3+CD4+CD25+FOXP3+CD25++CD45RA+) and activated Treg (aTreg, CD3+CD4+CD25+FOXP3+CD25+++CD45RA-) cells exhibit...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39083931
DOI: 10.1016/j.intimp.2024.112765

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