Article
Individuals with increased inflammatory response to ozone demonstrate muted signaling of immune cell trafficking pathways.
Respiratory research - 3 Oct 2012
Fry Rebecca C, Rager Julia E, Zhou Haibo, Zou Baiming, Brickey June W, Ting Jenny, Lay John C, Peden David B, Alexis Neil E
Abstract excerpt
BACKGROUND: Exposure to ozone activates innate immune function and causes neutrophilic (PMN) airway inflammation that in some individuals is robustly elevated. The interplay between immuno-inflammatory function and genomic signaling in those with heightened inflammatory responsiveness to ozone is not well understood. OBJECTIVES: Determine baseline predictors and post exposure discriminators for the...
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