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Article

Foxp3 promoter methylation impairs suppressive function of regulatory T cells in biliary atresia

22 Sept 2016

Abstract excerpt

Biliary atresia (BA) is characterized by progressive inflammation of the biliary system leading to liver cirrhosis, necessitating liver transplantation in pediatric patients. Various cell types have been reported to participate in the proinflammatory response in rhesus rotavirus (RRV)-induced BA mouse models, including T helper (Th) 1, Th2, Th17, CD8 + T cells, and natural killer cells. The immune suppressive...

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PMID: 27659419
DOI: 10.1152/ajpgi.00032.2016

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