Increased CD4+CD45RA-FoxP3low cells alter the balance between Treg and Th17 cells in colitis mice.

doi:10.3748/wjg.v22.i42.9356

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Article

Increased CD4+CD45RA-FoxP3low cells alter the balance between Treg and Th17 cells in colitis mice.

World journal of gastroenterology - 14 Nov 2016

Ma Ya-Hui, Zhang Jie, Chen Xue, Xie You-Fu, Pang Yan-Hua, Liu Xin-Juan

Abstract excerpt

AIM: To investigate the role of regulatory T cell (Treg) subsets in the balance between Treg and T helper 17 (Th17) cells in various tissues from mice with dextran sulfate sodium-induced colitis. METHODS: Treg cells, Treg cell subsets, Th17 cells, and CD4+CD25+FoxP3+IL-17+ cells from the lamina propria of colon (LPC) and other ulcerative colitis (UC) mouse tissues were evaluated by flow cytometry. Forkhead box...

Topics

Animals
CD4 Lymphocyte Count
Colitis, Ulcerative
Colon
Dextran Sulfate
Disease Models, Animal
Forkhead Transcription Factors
Gene Expression Regulation
Interleukin-17
Leukocyte Common Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice, Inbred C57BL

Nuclear Receptor Subfamily 1, Group F, Member 3

Phenotype

RNA, Messenger

T-Lymphocytes, Regulatory

Th17 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 27895423
DOI: 10.3748/wjg.v22.i42.9356
PMCID: PMC5107699

Genes

MLN
RORC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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