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Article

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.

The Journal of experimental medicine - 1 Sept 2008

Chong Mark M W, Rasmussen Jeffrey P, Rudensky Alexander Y, Rundensky Alexander Y, Littman Dan R

Abstract excerpt

MicroRNAs (miRNAs) are implicated in the differentiation and function of many cell types. We provide genetic and in vivo evidence that the two RNaseIII enzymes, Drosha and Dicer, do indeed function in the same pathway. These have previously been shown to mediate the stepwise maturation of miRNAs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18725527
DOI: 10.1084/jem.20081219
PMCID: PMC2526196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18725527-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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