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Article

Association between polymorphisms of the insulin-degrading enzyme gene and late-onset Alzheimer disease.

Journal of geriatric psychiatry and neurology - 1 Jun 2015

Wang Shitao, He Feiyan, Wang Ying

Abstract excerpt

The insulin-degrading enzyme (IDE) gene is a strong positional and biological candidate for late-onset Alzheimer disease (LOAD) susceptibility, with recent studies independently demonstrating an association between IDE gene variants and LOAD. However, previous data have been controversial. To investigate the relationship between IDE gene polymorphisms and LOAD risk, a case-control association study of 406 Han...

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PMID: 25414272
DOI: 10.1177/0891988714554707

Genes

IDE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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