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Article

The association between two single nucleotide polymorphisms within the insulin-degrading enzyme gene and Alzheimer's disease in a Chinese Han population.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia - 1 May 2012

Cui Pei-Jing, Cao Li, Wang Ying, Deng Yu-Lei, Xu Wei, Wang Gang, Zhang Yu, Zheng Lan, Fei Qing-Zhou, Zhang Ting, Chen Sheng-Di

Abstract excerpt

Several previous studies on the relationship between the insulin-degrading enzyme (IDE) gene and Alzheimer's disease (AD) have connected certain genetic variants to late-onset AD, in the absence of the apolipoprotein E (APOE)ε4 allele. However, the conclusions of these studies remain controversial. We investigated the association between two polymorphisms of IDE with AD in the Chinese population and found that...

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Source

Identifiers

PMID: 22502914
DOI: 10.1016/j.jocn.2011.08.036

Genes

IDE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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