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Variants in the insulin-degrading enzyme gene are associated with metabolic syndrome in Chinese elders.

Metabolism: clinical and experimental - 1 Oct 2009

Lu Xiaozhe, Huang Yanyan, Liu Yun, Wu Xiaoyan, Shi Xiaomei

Abstract excerpt

Metabolic syndrome (MetS) is a cluster of metabolic abnormalities sharing potential common underlying mechanisms. Insulin-degrading enzyme (IDE) plays a primary role in insulin degradation and cellular insulin processing and therefore affects glucose and lipid metabolism. Genetic association studies have been focused on the relationship between the IDE gene and the development of MetS. To identify specific...

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PMID: 19592050
DOI: 10.1016/j.metabol.2009.04.027

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IDE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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