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Article

Association of insulin degrading enzyme gene polymorphisms with Alzheimer's disease: a meta-analysis.

The International journal of neuroscience - 1 May 2015

Cheng Huawei, Wang Lin, Shi Tianlu, Shang Yuping, Jiang Ling

Abstract excerpt

Alzheimer's disease (AD) is a chronic degenerative disorder. It is caused by both genetic and environmental factors. The association of Insulin Degrading Enzyme (IDE) genotypes rs4646953, rs2251101 and rs1544210 with AD has been detected, but the findings were conflicted, however, Apolipoprotein-E (APOE)-ε4 allele has been observed as a genetic risk factor for AD. To investigate the issue, a meta-analysis was...

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Source

Identifiers

PMID: 25105907
DOI: 10.3109/00207454.2014.941440

Genes

IDE
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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