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Insulin-degrading enzyme is genetically associated with Alzheimer’s disease in the Finnish population

11 May 2007

Abstract excerpt

The gene for insulin-degrading enzyme (IDE), which is located at chromosome 10q24, has been previously proposed as a candidate gene for late-onset Alzheimer's disease (AD) based on its ability to degrade amyloid beta-protein. Genotyping of single nucleotide polymorphisms (SNPs) in the IDE gene in Finnish patients with AD and controls revealed SNPs rs4646953 and rs4646955 to be associated with AD, conferring an...

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PMID: 17496198
DOI: 10.1136/jmg.2006.048470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Insulin-degrading enzyme is genetically associated with Alzheimer’s disease in the Finnish populationPMID 17496198Read ↗

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Insulin-degrading enzyme and Alzheimer disease: a genetic association study in the Han Chinese.Semantic proximity Read ↗

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Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene.Semantic proximity Read ↗

Association between polymorphisms of the insulin-degrading enzyme gene and late-onset Alzheimer disease.Semantic proximity Read ↗

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