Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NLRP3 polymorphism is associated with protection against human T-lymphotropic virus 1 infection.

Memorias do Instituto Oswaldo Cruz - 1 Nov 2014

Kamada Anselmo Jiro, Pontillo Alessandra, Guimarães Rafael Lima, Loureiro Paula, Crovella Sergio, Brandão Lucas André Cavalcanti

Abstract excerpt

Inter-individual heterogeneity in the response to human T-lymphotropic virus 1 (HTLV-1) infection has been partially attributed to host genetic background. The antiviral activity of the inflammasome cytoplasmic complex recognises viral molecular patterns and regulates immune responses via the activation of interleukin (IL)-1 family (IL-1, IL-18 and IL-33) members. The association between polymorphisms in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HTLV-I Infections

Share to Human T-lymphotropic virus 1

Share to Inflammasomes

Share to Interleukin-1

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Share to Protective Factors

Source

Identifiers

PMID: 25411003

Genes

NLRP3
NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NLRP3 polymorphism is associated with protection against human T-lymphotropic virus 1 infection.PMID 25411003Read ↗

A 3'UTR SNP in NLRP3 gene is associated with susceptibility to HIV-1 infection.Semantic proximity Read ↗

Polymorphisms in inflammasome' genes and susceptibility to HIV-1 infection.Semantic proximity Read ↗

Association of TLR3 single nucleotide polymorphisms with susceptibility to HTLV-1 infection in Iranian asymptomatic blood donors.Semantic proximity Read ↗

Antagonistic role of IL-1ß and NLRP3/IL-18 genetics in chronic HIV-1 infection.Semantic proximity Read ↗

A Common NLRC4 Gene Variant Associates With Inflammation and Pulmonary Function in Human Immunodeficiency Virus and TuberculosisSemantic proximity Read ↗

Inflammasome genes polymorphisms may influence the development of hepatitis C in the Amazonas, Brazil.Semantic proximity Read ↗

RNase L Activates the NLRP3 Inflammasome during Viral InfectionsSemantic proximity Read ↗

A common polymorphism in TLR3 confers natural resistance to HIV-1 infection.Semantic proximity Read ↗

The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production.Semantic proximity Read ↗

TLR7 rs179008 (A/T) and TLR7 rs3853839 (C/G) polymorphisms are associated with variations in IFN-α levels in HTLV-1 infection.Semantic proximity Read ↗

Chemokines SNPs in HIV-1+ Patients and Healthy Controls from Northeast Brazil: Association with Protection against HIV-1 Infection.Semantic proximity Read ↗

Genotypic and allelic distribution of IFN-γ +874T/A and TGF-β1 -509C/T single-nucleotide polymorphisms in human immunodeficiency virus-infected Thais.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.