Article
Association of TLR3 single nucleotide polymorphisms with susceptibility to HTLV-1 infection in Iranian asymptomatic blood donors.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2020
Habibabadi Hossein Mehrabi, Parsania Masoud, Pourfathollah Ali Akbar, Haghighat Setareh, Sharifi Zohreh
Abstract excerpt
INTRODUCTION: The human T-lymphotropic virus type 1 (HTLV-1) has a single-stranded RNA genome and expresses specific proteins that have oncogenic potential. Approximately 15 to 20 million people worldwide have been infected by this virus. Changes in protein or gene expression are the effects of single nucleotide polymorphisms (SNPs) within the Toll-like receptor 3 (TLR3) gene. The function and efficacy of signal...
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