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Article

Polymorphisms in inflammasome' genes and susceptibility to HIV-1 infection.

Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2012

Pontillo Alessandra, Oshiro Telma M, Girardelli Martina, Kamada Anselmo J, Crovella Sergio, Duarte Alberto J S

Abstract excerpt

The involvement of inflammasome genes in the susceptibility to HIV-1 infection was investigated. Twelve single nucleotide polymorphisms within NLRP1, NLRP3, NLRC4, CARD8, CASP1, and IL1B genes were analyzed in 150 HIV-1-infected Brazilian subjects and 158 healthy controls. The 2 polymorphisms rs10754558 in NLRP3 and rs1143634 in IL1B were significantly associated to the HIV-1 infection. These findings supported...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22227487
DOI: 10.1097/QAI.0b013e3182392ebe

Genes

NLRP3
CARD8
CASP1
NLRC4
NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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