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Article

SNV-PPILP: refined SNV calling for tumor data using perfect phylogenies and ILP.

Bioinformatics (Oxford, England) - 1 Apr 2015

van Rens Karen E, Mäkinen Veli, Tomescu Alexandru I

Abstract excerpt

MOTIVATION: Recent studies sequenced tumor samples from the same progenitor at different development stages and showed that by taking into account the phylogeny of this development, single-nucleotide variant (SNV) calling can be improved. Accurate SNV calls can better reveal early-stage tumors, identify mechanisms of cancer progression or help in drug targeting. RESULTS: We present SNV-PPILP, a fast and easy to...

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PMID: 25398608
DOI: 10.1093/bioinformatics/btu755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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