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Article

SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors.

Bioinformatics (Oxford, England) - 15 Mar 2010

Goya Rodrigo, Sun Mark G F, Morin Ryan D, Leung Gillian, Ha Gavin, Wiegand Kimberley C, Senz Janine, Crisan Anamaria, Marra Marco A, Hirst Martin, Huntsman David, Murphy Kevin P, Aparicio Sam, Shah Sohrab P

Abstract excerpt

MOTIVATION: Next-generation sequencing (NGS) has enabled whole genome and transcriptome single nucleotide variant (SNV) discovery in cancer. NGS produces millions of short sequence reads that, once aligned to a reference genome sequence, can be interpreted for the presence of SNVs. Although tools...

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Identifiers

PMID: 20130035
DOI: 10.1093/bioinformatics/btq040
PMCID: PMC2832826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20130035-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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