Article

VILOCA: Sequencing quality-aware haplotype reconstruction and mutation calling for short- and long-read data

2024-06-09

Abstract excerpt

RNA viruses exist in large heterogeneous populations within their host. The structure and diversity of virus populations affects disease progression and treatment outcomes. Next-generation sequencing allows detailed viral population analysis, but inferring diversity from error-prone reads is challenging. Here, we present VILOCA, a method for mutation calling and reconstruction of local haplotypes from short- and l...

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Literature Corpus work: 3f15847c-f009-55d0-b258-62c1943cdf08
DOI: 10.1101/2024.06.06.597712

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