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Article

Inference of tumor phylogenies with improved somatic mutation discovery.

Journal of computational biology : a journal of computational molecular cell biology - 1 Nov 2013

Salari Raheleh, Saleh Syed Shayon, Kashef-Haghighi Dorna, Khavari David, Newburger Daniel E, West Robert B, Sidow Arend, Batzoglou Serafim

Abstract excerpt

Next-generation sequencing technologies provide a powerful tool for studying genome evolution during progression of advanced diseases such as cancer. Although many recent studies have employed new sequencing technologies to detect mutations across multiple, genetically related tumors, current methods do not exploit available phylogenetic information to improve the accuracy of their variant calls. Here, we present...

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Identifiers

PMID: 24195709
DOI: 10.1089/cmb.2013.0106
PMCID: PMC3822366

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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