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Article

Mesothelioma patients with germline BAP1 mutations have 7-fold improved long-term survival.

Carcinogenesis - 1 Jan 2015

Baumann Francine, Flores Erin, Napolitano Andrea, Kanodia Shreya, Taioli Emanuela, Pass Harvey, Yang Haining, Carbone Michele

Abstract excerpt

BRCA1-associated protein-1 (BAP1) mutations cause a new cancer syndrome, with a high rate of malignant mesothelioma (MM). Here, we tested the hypothesis that MM associated with germline BAP1 mutations has a better prognosis compared with sporadic MM. We compared survival among germline BAP1 mutation MM patients with that of all MM (N = 10 556) recorded in the United States Surveillance, Epidemiology, and End...

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Source

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Identifiers

PMID: 25380601
DOI: 10.1093/carcin/bgu227
PMCID: PMC4291047

Genes

BAP1
BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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