Article
PICALM and CR1 variants are not associated with sporadic Alzheimer's disease in Chinese patients.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
Li Hong-Lei, Shi Sheng-Sheng, Guo Qi-Hao, Ni Wang, Dong Yi, Liu Ying, Sun Yi-Min, Bei-Wang, Lu Shen-Ji, Hong Zhen, Wu Zhi-Ying
Abstract excerpt
Alzheimer's disease (AD) is the most common form of senile dementia, and the overall prevalence increases exponentially with age. It is well known that genetic variants may play an important role in the pathogenesis of this disorder. Recently, two independent large-scale genome-wide association studies (GWAS) identified 3 novel single nucleotide polymorphisms (SNPs) (rs11136000 within CLU, rs3851179 within PICALM...
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