Article
A cholesterol consensus motif is required for efficient intracellular transport and raft association of a group 2 HA from influenza virus.
The Biochemical journal - 15 Jan 2015
de Vries Maren, Herrmann Andreas, Veit Michael
Abstract excerpt
The HA (haemagglutinin) of influenza viruses must be recruited to membrane rafts to perform its function in membrane fusion and virus budding. We previously showed using FRET that deletion of the two raft-targeting features of HA, S-acylation at the cytoplasmic tail and the hydrophobic amino acid...
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