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Article

Features of influenza HA required for apical sorting differ from those required for association with DRMs or MAL.

Traffic (Copenhagen, Denmark) - 1 Dec 2003

Tall Renee D, Alonso Miguel A, Roth Michael G

Abstract excerpt

The influenza virus hemagglutinin (HA) is sorted to the apical membrane in polarized epithelial cells and associates with detergent-resistant membranes (DRMs). By systematic mutagenesis of the transmembrane residues, we show that hemagglutinin requires 10 contiguous transmembrane amino acids to enter detergent-resistant membranes and that the surface of the trimeric hemagglutinin transmembrane domain facing the...

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Source

Identifiers

PMID: 14617347
DOI: 10.1046/j.1398-9219.2003.0138.x

Genes

MAL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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