Article
Time to seroconversion in HIV-exposed subjects carrying protective versus non protective KIR3DS1/L1 and HLA-B genotypes.
PloS one - 1 Jan 2014
Tallon Benjamin J M, Bruneau Julie, Tsoukas Christos M, Routy Jean-Pierre, Kiani Zahra, Tan Xianming, Bernard Nicole F
Abstract excerpt
Natural killer (NK) cells play a role in the clearance of viral infections. Combinations of alleles at the polymorphic HLA-B locus and the NK cell surface killer immunoglobulin-like receptor locus KIR3DL1/S1 have been shown to influence time to AIDS in HIV-infected individuals and risk of seroconversion in HIV exposed seronegative (HESN) subjects. Here, we assessed time to seroconversion or duration of...
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