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Article

A pharmacogenetic association between a variation in calpain 10 (CAPN10) gene and the response to metformin treatment in patients with type 2 diabetes.

European journal of clinical pharmacology - 1 Jan 2015

Tkáč Ivan, Javorský Martin, Klimčáková Lucia, Židzik Jozef, Gaľa Igor, Babjaková Eva, Schroner Zbynek, Štolfová Mária, Hermanová Hana, Habalová Viera

Abstract excerpt

PURPOSE: The aim of the present study was to investigate possible associations of the single-nucleotide variants in six genes encoding the key molecules mediating the metformin pharmacodynamic effect with the response to treatment with metformin in patients with type 2 diabetes. METHODS: One hundred forty-eight drug-naïve patients with type 2 diabetes were included in the study. PRKAA1 rs249429, STK11 rs741765,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25327507
DOI: 10.1007/s00228-014-1774-y

Genes

CAPN10
PCK1
PRKAA1
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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