Article
Haplotype association of calpain 10 gene variants with type 2 diabetes mellitus in an Irish sample.
Irish journal of medical science - 1 Jun 2010
Alsaraj F, O'Gorman D, McAteer S, McDermott J, Hawi Z, Sreenan S
Abstract excerpt
BACKGROUND: Calpain 10 (CAPN10) gene may contribute to the pathogenesis of type 2 diabetes mellitus (T2DM). AIM: To examine the contribution of four CAPN10 gene variants to T2DM risk in an Irish sample. METHODS: Genotyping of marker 19 insertion-deletion (ins/del) and three CAPN10 variants, rs3792267, rs3749166 and rs5030952 at the CAPN10 gene was performed in 236 T2DM subjects and 120 controls. Allelic,...
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