Article
Variations in the calpain-10 gene are associated with the risk of type 2 diabetes and hypertension in northern Han Chinese population.
Chinese medical journal - 20 Dec 2007
Chen Shu-feng, Lu Xiang-feng, Yan Wei-Li, Huang Jian-feng, Gu Dong-feng
Abstract excerpt
BACKGROUND: Calpain-10 (CAPN10) has been identified as a susceptibility gene in type 2 diabetes mellitus (T2DM) and insulin resistance. The present study aimed to identify the effects of genetic variations in the CAPN10 gene on the development of type 2 diabetes and hypertension in northern Han Chinese population. METHODS: We performed a case-control study and genotyped single nucleotide polymorphism (SNP)-44,...
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