Article
A case-control study on the association of common variants of CAPN10 gene and the risk of type 2 diabetes in an Iranian population.
Clinical laboratory - 1 Jan 2014
Maleki Farajollah, Haghani Karimeh, Shokouhi Shabnam, Mahmoodi Khalil, Sayehmiri Kourosh, Mahdieh Nejat, Bakhtiyari Salar
Abstract excerpt
BACKGROUND: Calpain-10 is a ubiquitously expressed protease that serves as an intracellular calcium-dependent cysteine protease and is regarded to be one of the candidate genes for type 2 diabetes mellitus (T2DM). We aimed to identify the association of the common variants of this gene and the risk of T2DM in the Kurdish ethnic group of Iran. METHODS: Study groups included 173 T2DM and 173 normoglycemic subjects....
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