Article
Calpain 10 SNP-44 gene polymorphism affects susceptibility to type 2 diabetes mellitus and diabetic-related conditions.
Genetic testing - 1 Jun 2008
Demirci Huseyin, Yurtcu Erkan, Ergun Mehmet Ali, Yazici Ayse Canan, Karasu Cimen, Yetkin Ilhan
Abstract excerpt
The association of the gene encoding calpain 10 with type 2 diabetes mellitus (T2DM) has been reported. In this study we aimed to evaluate the association of SNP-19,-44, and -63 polymorphisms of calpain 10 with type 2 diabetes and diabetic-related conditions, such as diabetic retinopathy, nephropathy, and neuropathy in a Turkish population. The study group included 202 patients (133 female and 69 male) with T2DM,...
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