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Article

Computational Analysis of Single Nucleotide Polymorphisms Associated with Altered Drug Responsiveness in Type 2 Diabetes.

International journal of molecular sciences - 25 Jun 2016

Costa Valerio, Federico Antonio, Pollastro Carla, Ziviello Carmela, Cataldi Simona, Formisano Pietro, Ciccodicola Alfredo

Abstract excerpt

Type 2 diabetes (T2D) is one of the most frequent mortality causes in western countries, with rapidly increasing prevalence. Anti-diabetic drugs are the first therapeutic approach, although many patients develop drug resistance. Most drug responsiveness variability can be explained by genetic causes. Inter-individual variability is principally due to single nucleotide polymorphisms, and differential drug...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27347941
DOI: 10.3390/ijms17071008
PMCID: PMC4964384

Genes

CAPN10
ABCC8
GPR35
IRS1
KCNJ11
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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