Article
Refinement of schizophrenia GWAS loci using methylome-wide association data.
Human genetics - 1 Jan 2015
Kumar Gaurav, Clark Shaunna L, McClay Joseph L, Shabalin Andrey A, Adkins Daniel E, Xie Linying, Chan Robin, Nerella Srilaxmi, Kim Yunjung, Sullivan Patrick F, Hultman Christina M, Magnusson Patrik K E, Aberg Karolina A, van den Oord Edwin J C G
Abstract excerpt
Recent genome-wide association studies (GWAS) have made substantial progress in identifying disease loci. The next logical step is to design functional experiments to identify disease mechanisms. This step, however, is often hampered by the large size of loci identified in GWAS that is caused by linkage disequilibrium between SNPs. In this study, we demonstrate how integrating methylome-wide association study...
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