Article
Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes.
European journal of human genetics : EJHG - 1 Sept 2012
de Jong Simone, van Eijk Kristel R, Zeegers Dave W L H, Strengman Eric, Janson Esther, Veldink Jan H, van den Berg Leonard H, Cahn Wiepke, Kahn René S, Boks Marco P M, Ophoff Roel A
Abstract excerpt
There is genetic evidence that schizophrenia is a polygenic disorder with a large number of loci of small effect on disease susceptibility. Genome-wide association studies (GWASs) of schizophrenia have had limited success, with the best finding at the MHC locus at chromosome 6p. A recent effort of the Psychiatric GWAS consortium (PGC) yielded five novel loci for schizophrenia. In this study, we aim to highlight...
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