Article
Integration analysis of methylation quantitative trait loci and GWAS identify three schizophrenia risk variants.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2020
Yu Hao, Cheng Weiqiu, Zhang Xiao, Wang Xin, Yue Weihua
Abstract excerpt
Genome-wide association studies (GWAS) have identified hundreds of genetic variants associated with schizophrenia (SCZ). However, prioritizing risk variants and regulatory elements for follow-up functional studies remains a major challenge. Therefore, we performed an integrated analysis to identify variants who affect methylation levels of nearby genes and contribute to the risk of SCZ, and to explore the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
