Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pristane-induced granulocyte recruitment promotes phenotypic conversion of macrophages and protects against diffuse pulmonary hemorrhage in Mac-1 deficiency.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2014

Shi Yiqin, Tsuboi Naotake, Furuhashi Kazuhiro, Du Qiuna, Horinouchi Asuka, Maeda Kayaho, Kosugi Tomoki, Matsuo Seiichi, Maruyama Shoichi

Abstract excerpt

Diffuse pulmonary hemorrhage (DPH) is an uncommon but critical complication of systemic lupus erythematosus. Peritoneal administration of 2,6,10,14-tetramethylpentadecane (pristane) can recapitulate a lupus-like syndrome in mice, which can develop into DPH within a few weeks, especially in C57BL/6 mice. Mac-1 (CD11b/CD18), a leukocyte adhesion molecule, is known to play a role in inflammation by regulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation
Share to Granulocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemorrhage

Share to Interleukin-13

Share to Interleukin-4

Share to Macrophage-1 Antigen

Share to Peritoneal Cavity

Share to Terpenes

Source

Identifiers

PMID: 25281714
DOI: 10.4049/jimmunol.1401051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pristane-induced granulocyte recruitment promotes phenotypic conversion of macrophages and protects against diffuse pulmonary hemorrhage in Mac-1 deficiency.PMID 25281714Read ↗

TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine LupusSemantic proximity Read ↗

Phenotypic and functional alterations of peritoneal macrophages in lupus-prone mice.Semantic proximity Read ↗

IL-1α induces CD11b(low) alveolar macrophage proliferation and maturation during granuloma formation.Semantic proximity Read ↗

Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice.Semantic proximity Read ↗

Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype.Semantic proximity Read ↗

Macrophage Migration Inhibitory Factor deficiency attenuates kidney Injury by downregulating cytokines via CYR61 in lupus-prone mice induced by pristane.Semantic proximity Read ↗

Circulating CSF-1 promotes monocyte and macrophage phenotypes that enhance lupus nephritis.Semantic proximity Read ↗

Neutrophils contribute to ER stress in lung epithelial cells in the pristane-induced diffuse alveolar hemorrhage mouse modelSemantic proximity Read ↗

Structure and function of renal macrophages and dendritic cells from lupus-prone mice.Semantic proximity Read ↗

Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP.Semantic proximity Read ↗

Triggering receptor expressed on myeloid cells-1 (TREM-1) deficiency augments BAFF production to promote lupus progression.Semantic proximity Read ↗

Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockadeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.