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Article

Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype.

Prostaglandins & other lipid mediators - 1 Dec 2013

Rostoker Ran, Yaseen Hiba, Schif-Zuck Sagie, Lichtenstein Rachel G, Rabinovich Gabriel A, Ariel Amiram

Abstract excerpt

During the resolution of inflammation macrophages undergo functional changes upon exposure to pro-resolving agents in their microenvironment. Primarily, engulfment of apoptotic polymorphonuclear (PMN) cells promotes conversion of macrophages toward a pro-resolving phenotype characterized by reduced CD11b expression. These macrophages are not phagocytic, do not respond to TLR ligands, and express relatively high...

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PMID: 23954858
DOI: 10.1016/j.prostaglandins.2013.08.001

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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