Article
Phenotypic and functional alterations of peritoneal macrophages in lupus-prone mice.
Molecular biology reports - 1 Jun 2022
Tejon Gabriela, Valdivieso Nicolás, Flores-Santibañez Felipe, Barra-Valdebenito Verónica, Martínez Víctor, Rosemblatt Mario, Sauma Daniela, Bono María Rosa
Abstract excerpt
BACKGROUND: Several studies have demonstrated the contribution of innate immune cells, including macrophages, in promoting systemic lupus erythematosus (SLE). Macrophages, one of the most abundant cell populations in the peritoneal cavity, are considered multifunctional cells with phenotypic plasticity. However, the functional properties of peritoneal macrophages in steady-state and during the progression of SLE...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.