PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.

doi:10.1111/jgh.12540

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Article

PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.

Journal of gastroenterology and hepatology - 1 Jan 2014

Friedrich Kilian, Wannhoff Andreas, Kattner Stefan, Brune Maik, Hov Johannes Roksund, Weiss Karl Heinz, Antoni Christoph, Dollinger Matthias, Neumann-Haefelin Christoph, Seufferlein Thomas, Schemmer Peter, Schirmacher Peter, Stremmel Wolfgang, Gotthardt Daniel Nils

Abstract excerpt

BACKGROUND AND AIMS: The rs738409 variant (I148M) of the patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene is associated with several liver malfunctions. Its impact on end-stage liver disease has not been addressed yet. METHODS: The I148M polymorphism was genotyped in a well-characterized cohort of 421 Caucasian patients and retrospectively analyzed from the time of enrollment at...

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Identifiers

PMID: 25273282
DOI: 10.1111/jgh.12540

Genes

PNPLA3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.PMID 25273282Read ↗

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