Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages.

PloS one - 1 Jan 2014

Weiden Michael D, Hoshino Satomi, Levy David N, Li Yonghua, Kumar Rajnish, Burke Sean A, Dawson Rodney, Hioe Catarina E, Borkowsky William, Rom William N, Hoshino Yoshihiko

Abstract excerpt

While exploring the effects of aerosol IFN-γ treatment in HIV-1/tuberculosis co-infected patients, we observed A to G mutations in HIV-1 envelope sequences derived from bronchoalveolar lavage (BAL) of aerosol IFN-γ-treated patients and induction of adenosine deaminase acting on RNA 1 (ADAR1) in t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Deaminase
Share to Bronchoalveolar Lavage Fluid
Share to Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to Interferon-gamma

Share to Macrophages, Alveolar

Share to Tuberculosis

Share to Viral Tropism

Source

Open in PubMed Open full text

Identifiers

PMID: 25272020
DOI: 10.1371/journal.pone.0108476
PMCID: PMC4182706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25272020-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adenosine deaminase acting on RNA-1 (ADAR1) inhibits HIV-1 replication in human alveolar macrophages.PMID 25272020Read ↗

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infectionSemantic proximity Read ↗

Double-Stranded RNA Adenosine Deaminases Enhance Expression of Human Immunodeficiency Virus Type 1 ProteinsSemantic proximity Read ↗

RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophagesSemantic proximity Read ↗

Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein KinaseSemantic proximity Read ↗

ADAR1 affects HCV infection by modulating innate immune response.Semantic proximity Read ↗

Elevated m 6 A RNA Modifications Associate with Immune Dysregulation and Cancer in People with HIV-1Semantic proximity Read ↗

ADAR1 restricts LINE-1 retrotranspositionSemantic proximity Read ↗

A-to-G hypermutation in the genome of lymphocytic choriomeningitis virus.Semantic proximity Read ↗

Replication-competent HIV-1 in human alveolar macrophages and monocytes despite nucleotide pools with elevated dUTPSemantic proximity Read ↗

ADAR1 Interacts with PKR during Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral ReplicationSemantic proximity Read ↗

ADAR1 is a novel multi targeted anti-HIV-1 cellular protein.Semantic proximity Read ↗

<i>N</i> <sup>6</sup> -methyladenosine modification of HIV-1 RNA evades RIG-I-mediated sensing to suppresses type-I interferon induction in monocytic cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.