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Article

ADAR1 restricts LINE-1 retrotransposition

21 Sept 2016

Abstract excerpt

Adenosine deaminases acting on RNA (ADARs) are involved in RNA editing that converts adenosines to inosines in double-stranded RNAs. ADAR1 was demonstrated to be functional on different viruses exerting either antiviral or proviral effects. Concerning HIV-1, several studies showed that ADAR1 favors viral replication. The aim of this study was to investigate the composition of the ADAR1 ribonucleoprotein complex...

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PMID: 27658966
DOI: 10.1093/nar/gkw834

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