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Article

ADAR1 is a novel multi targeted anti-HIV-1 cellular protein.

Virology - 20 Jan 2012

Biswas Nabanita, Wang Tianyi, Ding Ming, Tumne Ashwin, Chen Yue, Wang Qingde, Gupta Phalguni

Abstract excerpt

We examined the antiviral activity of ADAR1 against HIV-1. Our results indicated that ADAR1 in a transfection system inhibited production of viral proteins and infectious HIV-1 in various cell lines including 293T, HeLa, Jurkat T and primary CD4+ T cells, and was active against a number of X4 and R5 HIV-1 of different clades. Further analysis showed that ADAR1 inhibited viral protein synthesis without any effect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22104209
DOI: 10.1016/j.virol.2011.10.024
PMCID: PMC3253023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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