Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase

14 Apr 2011

Abstract excerpt

Adenosine deaminase acting on RNA 1 (ADAR1) is a double-stranded RNA binding protein and RNA-editing enzyme that modifies cellular and viral RNAs, including coding and noncoding RNAs. This interferon (IFN)-induced protein was expected to have an antiviral role, but recent studies have demonstrated that it promotes the replication of many RNA viruses. The data from these experiments show that ADAR1 directly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA regulation and disease
Share to RNA Research and Splicing
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21490091
DOI: 10.1128/jvi.00240-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein KinasePMID 21490091Read ↗

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infectionSemantic proximity Read ↗

ADARs and the Balance Game between Virus Infection and Innate Immune Cell ResponseSemantic proximity Read ↗

Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1p150Semantic proximity Read ↗

ADAR1: “Editor-in-Chief” of Cytoplasmic Innate ImmunitySemantic proximity Read ↗

ADAR1 affects HCV infection by modulating innate immune response.Semantic proximity Read ↗

Double-Stranded RNA Adenosine Deaminases Enhance Expression of Human Immunodeficiency Virus Type 1 ProteinsSemantic proximity Read ↗

Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human DiseasesSemantic proximity Read ↗

Increased RNA Editing and Inhibition of Hepatitis Delta Virus Replication by High-Level Expression of ADAR1 and ADAR2Semantic proximity Read ↗

Adenosine Deaminases Acting on RNA, RNA Editing, and Interferon ActionSemantic proximity Read ↗

ADAR Editing in Viruses: An Evolutionary Force to Reckon withSemantic proximity Read ↗

RNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKR.Semantic proximity Read ↗

The role of RNA editing by ADAR1 in prevention of innate immune sensing of self-RNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.