Article
A-to-G hypermutation in the genome of lymphocytic choriomeningitis virus.
Journal of virology - 1 Jan 2007
Zahn Roland C, Schelp Ina, Utermöhlen Olaf, von Laer Dorothee
Abstract excerpt
The interferon-inducible adenosine deaminase that acts on double-stranded RNA (ADAR1-L) has been proposed to be one of the antiviral effector proteins within the complex innate immune response. Here, the potential role of ADAR1-L in the innate immune response to lymphocytic choriomeningitis virus (LCMV), a widely used virus model, was studied. Infection with LCMV clearly upregulated ADAR1-L expression and...
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