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Article

Genome editing a mouse locus encoding a variant histone, H3.3B, to report on its expression in live animals.

Genesis (New York, N.Y. : 2000) - 1 Dec 2014

Wen Duancheng, Noh Kyung-Min, Goldberg Aaron D, Allis C David, Rosenwaks Zev, Rafii Shahin, Banaszynski Laura A

Abstract excerpt

Chromatin remodeling via incorporation of histone variants plays a key role in the regulation of embryonic development. The histone variant H3.3 has been associated with a number of early events including formation of the paternal pronucleus upon fertilization. The small number of amino acid differences between H3.3 and its canonical counterparts (H3.1 and H3.2) has limited studies of the developmental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25262655
DOI: 10.1002/dvg.22827
PMCID: PMC5844183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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