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Article

The double face of the histone variant H3.3.

Cell research - 1 Mar 2011

Szenker Emmanuelle, Ray-Gallet Dominique, Almouzni Geneviève

Abstract excerpt

Histone proteins wrap DNA to form nucleosome particles that compact eukaryotic genomes while still allowing access for cellular processes such as transcription, replication and DNA repair. Histones exist as different variants that have evolved crucial roles in specialized functions in addition to their fundamental role in packaging DNA. H3.3--a conserved histone variant that is structurally very close to the...

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PMID: 21263457
DOI: 10.1038/cr.2011.14
PMCID: PMC3193428

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