Article
Expression patterns and post-translational modifications associated with mammalian histone H3 variants.
The Journal of biological chemistry - 6 Jan 2006
Hake Sandra B, Garcia Benjamin A, Duncan Elizabeth M, Kauer Monika, Dellaire Graham, Shabanowitz Jeffrey, Bazett-Jones David P, Allis C David, Hunt Donald F
Abstract excerpt
Covalent histone modifications and the incorporation of histone variants bring about changes in chromatin structure that in turn alter gene expression. Interest in non-allelic histone variants has been renewed, in part because of recent work on H3 (and other) histone variants. However, only in mammals do three non-centromeric H3 variants (H3.1, H3.2, and H3.3) exist. Here, we show that mammalian cell lines can be...
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