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Article

Genes of the month: H3.3 histone genes: H3F3A and H3F3B.

Journal of clinical pathology - 1 Dec 2021

Kumar Vishnu Chandra, Pai Rekha

Abstract excerpt

Histones constitute the chief protein component of DNA. They help to maintain chromatin structure and regulate gene expression. The long double-stranded DNA molecule winds around histone octamers to form nucleosomes which serve the purpose of compacting DNA within the confines of the nuclear membrane. There are five major types of histones, namely H1/H5, H2, H3 and H4. H3.3 is a subtype of H3 histone and can be...

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Identifiers

PMID: 34667098
DOI: 10.1136/jclinpath-2021-207857

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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