Article
SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.
Human immunology - 1 Nov 2014
Sun Chengjun, Zhi Dijing, Shen Shuixian, Luo Feihong, Sanjeevi Carani B
Abstract excerpt
OBJECTIVE: Toll-like receptors (TLRs) recognize a wide range of pathogen-associated molecular patterns (PAMP) and mount the initiation of immune response. Single nucleotide polymorphisms (SNPs) in exons of genes encoding TLRs might be responsible for the generation of an abnormal immune response which could lead to autoimmune diseases. In this study, we investigated the SNPs in TLRs in a Chinese population, and...
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