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Article

Association of Toll-like Receptor 4 Gene polymorphisms with susceptibility to type 2 diabetes mellitus in the Chinese population.

Journal of diabetes - 1 Jul 2015

Peng Danfeng, Jiang Feng, Zhang Rong, Tang Shanshan, Chen Miao, Yan Jing, Sun Xue, Luo Yi, Hu Cheng, Jia Weiping

Abstract excerpt

BACKGROUND: Toll-like receptor 4 (TLR4) plays an important role in innate immunity. Activation of innate immune response and subsequent chronic low-grade inflammation are thought to be involved in the pathogenesis of type 2 diabetes. In this study, we aimed to investigate the association of TLR4 variants with type 2 diabetes in the Chinese population. METHODS: Seven tag single nucleotide polymorphisms (SNPs) of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25104099
DOI: 10.1111/1753-0407.12206

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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